Overview
This course includes both hands-on and theory components covering topics such as clarification, ultrafiltration/diafiltration, viral clearance, and chromatography. Participants will be introduced to the basics of filtration and chromatography in a theory session before building on this knowledge and performing these operations in the hands-on component.

Who should take this course?
Individuals who are new to downstream processing, including operators, technical staff, engineers, and managers who need to enhance their basic knowledge of actual operations in a modern downstream processing biopharmaceutical plant.

Key Topics

• Depth Filtration
• Sterile Filtration
• Tangential Flow Filtration (Ultrafiltration, Diafiltration & Microfiltration)
• Chromatography and Column Packing

Learning Objectives

• Describe the different types of chromatography operations used in a bioprocessing facility
• Pack chromatography column utilizing a flow pack method
• Describe the key operations of ultrafiltration and diafiltration
• Perform protein concentration and buffer exchange using UF/DF systems
• Assessment 

Delivery

• In English
• 1 half-day of virtual theoretical training on April 25 2025
• 2 days in-person, hands-on training at the CASTL Biomanufacturing Training Facility in Charlottetown on May 1-2nd 2025