Overview
This course includes both hands-on and theory components covering topics such as clarification, ultrafiltration/diafiltration, viral clearance, and chromatography. Participants will be introduced to the basics of filtration and chromatography in a theory session before building on this knowledge and performing these operations in a practical component.

Who should take thus course?
Individuals who are new to downstream processing, including operators, technical staff, engineers, and managers who need to enhance their basic knowledge of actual operations in a modern downstream processing biopharmaceutical plant.

Key Topics

• Depth Filtration
• Sterile Filtration
• Tangential Flow Filtration (Ultrafiltration, Diafiltration and Microfiltration)
• Chromatography and Column Packing

Learning Objectives

• Describe the different types of chromatography operations used in a bioprocessing facility
• Pack chromatography column utilizing a flow pack method
• Describe the key operations of ultrafiltration and diafiltration
• Perform protein concentration and buffer exchange using UF/DF systems
• Assessment 

Delivery

• In English
• 1 half-day of virtual theoretical training on February 14 2025
• 2 days in-person, hands-on practical at the CASTL Biomanufacturing Training Facility in Montreal on February 20-21st 2025